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The Chalmers Research Group (CRG) established in 1998, is an academic research group located in the Children's Hospital of Eastern Ontario Research Institute (CHEO RI), Ottawa, Ontario Canada and is affiliated with the University of Ottawa. It is engaged exclusively in evidence synthesis in healthcare and related methods research. CRG is committed to developing high quality systematic reviews and health technology assessments, and has garnered international recognition having conducted research for and training to local, provincial, national and international stakeholders.

It is home to the international Cochrane Collaboration's Bias Methods group (BMG) and the international group for the Consolidated of Reporting Initiatives for Randomized Controlled Trials (CONSORT). It is also the coordinating base for the University of Ottawa's Evidence-based Practice Center (UO-EPC); a flagship research program funded by the U.S. Agency for Healthcare Research and Quality (AHRQ).